腹腔镜术联合醋酸曲普瑞林治疗子宫内膜异位症的87例临床效果观察

摘要

Objectives:To evaluate the clinical effect of laparoscopic surgery combined with triptorelin ace-tate in the treatment of endometriosis,in order to improve the clinical diagnosis and treatment.Methods:87 pa-tients with endometrial endometriosis from May 201 0 to May 201 3 were selected and divided into two groups:control group of 43 patients received laparoscopic surgery for treatment and the observation group (44 patients)received ad-ditional triporelin acetate treatment.The efficacy variable changes after treatment were observed.Results:In the control group,the response rate and total efficiency were 30.23% and 76.74% respectively.In the observation group,the response rate and total efficiency were 45.45% and 93.1 8% respectively.The difference between the two groups was statistically significant (P <0.05).Difference in pelvic pain,dysmenorrhea and dyspareunia points and CA -1 25,FSH,E2 level between the two groups before treatment was not statistically significant (P >0.05), while difference between before and after treatment was statistically significant (P <0.05 ),and difference after treatment was of more statistically significant difference (P <0.05).Conclusions:Laparoscopic surgery with trip-torelin acetate is of significant clinical effect in the treatment of endometriosis.%目的：探讨腹腔镜术联合醋酸曲普瑞林治疗子宫内膜异位症临床效果，以期提高临床诊治水平。方法：选取2010年5月至2013年5月87例子宫内膜异位症患者为研究对象，分成两组，对照组43例，予腹腔镜术治疗，观察组44例，加用醋酸曲普瑞林治疗，观察两组治疗后疗效指标变化情况。结果：疗效上，对照组缓解率30.23％，总有效率76.74％；观察组缓解率45.45％，总有效率93.18％，两组比较差异有统计学意义（P ＜0.05）。两组治疗前在盆腔痛、痛经和性交痛积分和 CA －125、FSH、E2水平比较差异无统计学意义（P ＞0.05），治疗后和治疗前比较差异有统计学意义（P ＜0.05），治疗后较治疗前比较差异更有统计学意义（P ＜0.05）。结论：腹腔镜术联合醋酸曲普瑞林治疗子宫内膜异位症临床效果显著。