Objective To understand the incidence, clinical features and influencing factors of anxiety and depression in the patients with cardiovascular diseases, and to provide evidences for clinical treatment. Methods The patients (n=1105) with cardiovascular diseases were chosen from Jan. 2012 to Mar. 2012, and they were all given psychological examination with the Hospital Anxiety and Depression Scale (HADS), Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) for reviewing the incidence of anxiety and depression. The relative risk factors were reviewed by using Logistic regression analysis, and curative effect of cardiovascular drugs combining psychological intervention was observed. Results Among included patients with cardiovascular diseases, those with anxiety and depression accounted for 22.81%(252/1105), and of them anxiety, for 53.97%(136/252), depression, for 31.35% (79/252), and anxiety combining depression, for 14.68% (37/252). Logistic regression analysis showed that health condition, working state and work fatigue extent were major risk factors of anxiety and depression (P<0.05). The effective rate of anti-anxiety-depression drugs combining psychological intervention reached 95.63%on the basis of cardiovascular drugs. Conclusion The incidence of anxiety and depression is higher in the patients with cardiovascular diseases, and the symptoms of anxiety and depression are influenced by many factors. The treatment of anti-anxiety-depression on the basis of cardiovascular drugs will be help to improve the whole condition of patients.%目的了解心血管疾病患者焦虑抑郁症状发病情况和临床特征并分析其影响因素，为临床治疗提供依据。方法纳入2012年1月～2012年3月1105例心血管疾病患者，所有患者均接受综合医院焦虑抑郁量表、汉密尔顿抑郁量表和汉密尔顿焦虑量表进行心理状况检测，评估焦虑、抑郁的发生率，采用Logistic回归分析对相关危险因素进行评价，观察在使用心血管药物治疗联合心理干预的治疗效果。结果所纳入心血管疾病患者中焦虑和抑郁患者占22.81%（252/1105），其中53.97%（136/252）为焦虑，31.35%（79/252）为抑郁，14.68%（37/252）同时合并焦虑和抑郁。多因素非条件Logistic回归分析显示：健康状况、工作状态和工作劳累程度是焦虑抑郁的主要危险因素（P＜0.05）。在使用心血管药物治疗的基础上合并使用抗焦虑抑郁药物同时配合心理干预治疗后总有效率达95.63%。结论心血管疾病住院患者中焦虑抑郁症状发病率较高，焦虑抑郁症状受到多种因素影响，在治疗心血管疾病的基础上进行抗焦虑抑郁治疗有助于改善患者整体状况。
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