超声三维斑点追踪技术评价非ST段抬高型急性冠状动脉综合征心功能的临床研究

摘要

Objective To evaluate the clinical significance of three-dimensional speckle tracking echocardiography in assessing cardiac function in patients with non-ST segment elevated acute coronary syndrome (NSTE-ACS).Methods 66 patients with NSTE-ACS and 20 normal subjects were analyzed by three-dimensional speckle tracing technique. The levels of Left ventricular global longitudinal strain (LVGLS), left ventricular global migration (LVGCS), left ventricular global radial strain (LVGRS), hs-CRP, triglyceride, cholesterol, low density lipoprotein and high density lipoprotein were measured.Results Compared with normal control group, LVGLS, LVGCS and LVGRS were significantly decreased in NSTE-ACS group (P<0.05), especially LVGLS (P=0.008). Compared with the normal control group, the high sensitivity C-reactive protein, triglyceride, cholesterol and low density lipoprotein were significantly increased and the density of high density lipoprotein was decreased in NSTE-ACS group, the difference was statistically significant.Conclusion Three-dimensional speckle tracking echocardiography can accurately and quantitatively evaluate the overall systolic function of patients with NSTE-ACS. LVGLS which is more specific.%目的 探讨应用超声三维斑点追踪技术评价非ST段抬高型急性冠状动脉综合征(NSTE-ACS)心功能的临床意义.方法 使用三维斑点追踪技术对NSTE-ACS患者66例及20例正常人进行分析,获得左室整体纵向应变(LVGLS)、圆周应变(LVGCS)、径向应变(LVGRS),对所有患者及对照组的高敏C反应蛋白(hs-CRP)、三酰甘油、胆固醇、低密度脂蛋白、高密度脂蛋白等指标的含量进行测定.结果 与正常对照组对比,NSTE-ACS组LVGLS、LVGCS、LVGRS明显减低,差异有统计学意义(P<0.05);以LVGLS差异更特异(P=0.008),高敏C反应蛋白、三酰甘油、胆固醇、低密度脂蛋白NSTE-ACS组较正常组明显升高,高密度脂蛋白降低,差异均有统计学意义.结论 超声三维斑点追踪技术可以准确、定量评价NSTE-ACS患者心脏整体收缩功能.其中纵向应变差异更特异.