Objective To compare the efficacy of surgery plus chemotherapy with surgery alone in the therapy of borderline ovarian tumors (BOT). Methods The clinical data of BOT patients who were confirmed by pathological examination after surgery from January 2006 to December 2011 were collected. The patients were divided into two groups according to the type of previous treatment strategies: 22 cases in the chemotherapy group (surgery plus chemotherapy) and 20 cases in the control group ( surgery alone). The two groups of patients were followed up, and the efficacy of them was analyzed. Results During the follow-up period, the survival rates of BOT in chemotherapy group and control group patients were 95. 5% (21/ 22) , 100% (20/20) respectively; the recurrence rates were 9. 1% (2/22) , 5. 0% (1/20) respectively. There were no significant differences in two groups ( P >0.05). The rate of pregnancy was significantly higher in chemotherapy group (55.6% , 5/9) than that of in the control group (22. 2% , 2/9) , but the results were not statistically significant ( P >0. 05). Conclusion Compared with the simple operative treatment, the postoperative chemotherapy could not effectively delay the recurrence, improve the survival and increase pregnancy rates of patients who accept fertility-sparing treatment in the short term.%目的 比较单纯手术治疗与手术联合化疗治疗交界性卵巢肿瘤的疗效.方法 2006年1月—2011年12月收治病理检查确诊的交界性卵巢肿瘤患者42例,根据治疗方法分为化疗组(手术联合化疗)22例、对照组(单纯手术治疗)20例,对2组患者进行随访,分析其疗效.结果 随访期间化疗组与对照组的5年生存率分别为95.5％(21/22)、100％(20/20),复发率分别为9.1％(2/22)、5.0％(1/20),妊娠率分别为55.6％(5/9)、22.2％ (2/9),2组比较差异均无统计学意义(P＞0.05).结论 与单纯手术治疗比较,术后辅助性化疗短期内不能明显延缓复发、提高患者的生存率及增加保留生育功能患者术后的妊娠率.
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