中国香港地区2型糖尿病患者阻塞性睡眠呼吸暂停的患病率和识别

摘要

目的 探讨患糖尿病的中国香港地区阻塞性睡眠呼吸暂停(OSA)的患病率和相关临床因素.方法 入选标准为18-75岁中国香港地区2型糖尿病患者且除外不稳定临床疾病、妊娠期糖尿病或正进行肾脏替代治疗者.结果:估计糖尿患者群中OSA的患病率是17.5%(男性24.7%,女性10.3%);睡眠呼吸暂停低通气指数(AHI)与BMI,老年,男性和舒张压独立相关;中重度OSA中需要≥3种抗高血压药物的校正优势比为2.48;血糖控制(HbA1c)和睡眠之间无明确关系.结论 OSA在患糖尿病的中国香港地区人群中有较高的患病率.%The aims of this study were to investigate the prevalence of OSA and the relative clinical factors in Chinese patients with DM. Inclusion criteria for patients were Chinese aged 18 to 75 years, with type 2 DM. Patients with unstable medical illnesses, gestational diabetes, or on renal replacement therapy were excluded. The estimated OSA prevalence in this diabetic cohort was 17. 5％ (24. 7％ in men, 10. 3％in women). Apnea hyponea index was associated independently with higher BMI, advanced age, male sex,and higher diastolic BP. The adjusted OR in patients requiring three or more antihypertensive drugs in moderate/severe OSA was 2. 48. No association between glycemic control (HbA1c) and sleep was identified. In conclusion, OSA is more prevalent in Chinese adults with DM than in the general population.