2型糖尿病患者降糖治疗过程中发生低血糖原因的观察

摘要

目的 探讨T2DM患者降糖治疗过程中发生低血糖的原因. 方法 对216例发生低血糖T2DM患者的临床资料进行回顾性分析,另选同期住院未发生低血糖T2DM患者216例,对收集的变量进行单因素分析. 结果 单因素x2检验分析结果显示,T2DM患者发生低血糖的变量分别为年龄、病程、FPG、HbA1c及BMI (P均＜0.05).导致低血糖的原因为饮食不合理(20.8％)、运动不适当(9.8％)及药物因素(69.4％). 结论 T2DM降糖治疗过程中低血糖的发生是多种因素作用的结果,在饮食、运动及药物综合因素中,药物因素是其主要原因.%Objective To explore the causes of hypoglycemia of T2DM patients during hypoglycemic agents treatment to provide guidance for the prevention of hypoglycemia in treating diabetes.Methods A retrospective analysis was carried out for a study on 216 T2DM cases with hypoglycemia during hospitalization.And 216 T2DM patients without hypoglycemia in hospitalization were selected as the control group.Thecollected variables'were used for a single factor analysis.Results The single factor analysis of the x2 test showed that the variables of hypoglycemia occurrence were age,duration of diabetes,FPG,HbA1c,and BMI (all P＜0.05).The causes of hypoglycemia were unreasonable diet (45 cases,20.8％),improper movement (21 cases,9.8％),and unsuitable use of hypoglycemic agents (150 cases,69.4％).Conclusion The occurrence of hypoglycemia in diabetic patients results from comprehensive effects of many factors.Drug overdose takes the largest proportion in all kinds of inducing factors leading to hypoglycemia.