超顺磁性氧化铁纳米颗粒应用于干细胞定向归巢中的研究进展

摘要

干细胞在组织器官的自我更新和修复过程中起重要作用.在外加磁场的作用下,用纳米磁铁颗粒标记干细胞,可增加干细胞的定向归巢和存留,从而放大干细胞的修复效应.本文就纳米磁铁颗粒靶向干细胞的原理,以及其在各种病理模型应用的研究进展作一综述.%Stem cells play an important role in self-renewal and repair of tissues and organs.Under the influence of the external magnetic field, labeling the stem cells with magnetic nanoparticles can increase the directional homing and retention of the stem cells, thereby amplifying the repair effect of the stem cells.In this paper, the principle of magnetic nanoparticles targeting stem cells and its progress in the application of various pathological models are reviewed.