A two-feed simulated moving bed(SMB) was proposed to utilize the stationary phase more effectively.Zone I is disconnected with zone II and zone III is disconnected with zone IV.Two feeds are added to zones I and III,while two desorbents are added to zones II and IV separately.The investigation on the movement of concentra-tion bands indicated that the tail of the strong retained solute and the front of the weak retained solute were eluted from zones I and III orderly,so the streams from zones I and III could be cut into different fractions to give the products with high purity.The two-feed SMB was used to separate α-tocopherol from its homologue mixture suc-cessfully,and could double the productivity if both feeds were identical to the feed in the conventional four-zone SMB.The solvent consumption could be reduced by reusing the middle fraction without solutes.
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