稳心颗粒治疗冠心病合并的心律失常疗效观察

摘要

Objective; To study the therapeutic effects of Buchang wenxin granules on arrhythmia in patients with coronary heart disease (CHD). Methods: A total of 90 CHD patients complicated frequent atrial premature beats, frequent ventricular premature beats and paroxysmal supraventricular tachycardia were randomly and equally divided into wenxin granules group (received routine therapy and Buchang wenxin granules) and routine treatment group (received routine therapy and gingko soft capsules). Therapeutic effects and incidence of arrhythmia of the two groups were compared and analyzed. Results: After treatment, clinical overall effective rate (84.2％ vs. 64.4％) was significantly higher, recurrence rate (15. 3％ vs. 50％) was significantly lower in wenxin granules group than those of routine treatment group, P＜0. 05 both; according to 24h dynamic electrocardiogram, frequent atrial premature beats [ (32±10) times/ 24h vs. (130±21) times/24h], frequent ventricular premature beats [ (28±8) times/24h vs. (135±26) times/24h] and paroxysmal supraventricular tachycardia [ (10±5) times/24h vs. (32±8) times/24h] significantly decreased in wenxin granules group compared with those of routine treatment group (P＜0. 01 all). Conclusion: Wenxin granules possesses definite therapeutic effects on frequent atrial premature beats, frequent ventricular premature beats and paroxysmal supraventricular tachycardia and the recurrence rate is low in patients with coronary heart disease.%目的:探讨步长稳心颗粒治疗冠心病心律失常的临床疗效.方法:90例患有冠心病合并频发房早、频发室早、阵发性室上速的患者被随机均分成稳心颗粒组(常规治疗+步长稳心颗粒)和常规治疗组(常规治疗+银杏软胶囊),比较两组疗效和心律失常发作次数.结果:治疗后,稳心颗粒组临床总有效率明显高于常规治疗组(84.2%比64.4%),复发率明显低于常规治疗组(15.3%比50%),P均<0.05;24h动态心电图检查,稳心颖粒组频发房早[(32±10)次/24h比(130±21)次/24h],频发室早[(28±8)次/24h比(135±26)次/24h]、阵发性室上速仁(10±5)次/24h比(32±8)次/24h]较常规治疗组明显减少(P均<0.01).结论:稳心颗粒治疗冠心病合并的频发房早、频发室早、阵发性室上速疗效确切,复发率低.