Objective: To investigate value of detection of Helicobacter pylori (HP) in treatment of coronary heart disease (CHD). Methods: According to age, a total of 192 CHD patients were divided into young and middle aged group (98 cases) and aged group (94 cases). All patients received 14C detection and each group was further divided into two subgroap according to results of 14C detection: young and middle aged HP negative group (54 cases), young and middle aged HP positive group (44 cases)i aged HP negative group (50 cases), aged HP positive group (44 cases) . All patients received CHD standard treatment and incidence of gastrointestinal bleeding was observed. Results: In one month, there was no significant difference in incidence rate of gastrointestinal bleeding between two subgroups of young and middle aged group (x2 = 0.486, P>0.05) ; in aged group, incidence rate of gastrointestinal bleeding in HP positive group was significant higher than that of HP negative group (15.91% vs. 2.00%, x2 = 4.166, P<0.05). Conclusion: Detection of Helicobacter pylori possesses certain value for predicting gastrointestinal bleeding.%目的:探讨在冠心病患者治疗过程中测定幽门螺杆菌(HP)的意义.方法:192例冠心病患者按照年龄分为中青年组(98例)和老年组(94例),均行14C检测,按照阳性和阴性结果各组又分为两个亚组:中青年HP阴性组(54例),中青年HP阳性组(44例),老年HP阴性组(50例),老年HP阳性组(44例).各组患者均接受冠心病的标准治疗方案,分别观察各组患者消化道出血发生的情况.结果:一个月内,中青年组的两亚组消化道出血发生率无显著差异(x2=0.486,P＞0.05)；老年组HP阳性者消化道出血发生率明显高于HP阴性者(15.91％比2.00％,x2=4.166,P＜0.05).结论:幽门螺杆菌测定对于预测老年冠心病患者的消化道出血有一定的参考作用.
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