miRNA与扩张型心肌病关系的研究进展

摘要

扩张型心肌病(DCM)是非缺血性心肌病中最普遍的类型,预后差,死亡率高.近年来的研究发现,非编码小分子RNA(miRNA)与DCM的病程密切相关.本文就miRNA的表达模式与DCM发展的相关研究进行综述.%Dilated cardiomyopathy (DCM) is the most frequent pattern of non-ischemic cardiomyopathy with poor prognosis and high mortality.Studies in recent years found that non-coding small RNA molecules (miRNA) were closely related to the clinical course of DCM.The present article made a review on the expression pattern of miRNA and development of DCM study.