Objective: To explore influence of rehabilitative exercise on left ventricular hypertrophy (LVH), diastolic function and blood pressure in patients with hypertension.Methods: A total of 120 patients diagnosed as essential hypertension complicated LVH in our hospital were enrolled.They were randomly and equally divided into routine treatment group (received routine antihypertensive treatment) and rehabilitative exercise group (received rehabilitative exercise based on routine antihypertensive medication).Blood pressure control rate on four, eight and 12 weeks after treatment, color Doppler echocardiographic outcomes before and 12 weeks after treatment were compared between two groups.Results: Blood pressure control rate after 12 weeks in rehabilitative exercise group was significantly higher than that of routine treatment group (76.7% vs.58.3%, P=0.03).Echocardiography indicated that compared with before treatment, there were significant improvements in left ventricular diastolic function and LVH indexes except left ventricular end-diastolic dimension in both groups after treatment, P<0.01 all;but there were no significant difference in left ventricular diastolic function and LVH indexes between two groups after treatment, P>0.05 all.Conclusion: Rehabilitative exercise training can significantly improve blood pressure control rate in patients with essential hypertension.Short-medium term exercise training fails to significantly improve left ventricular hypertrophy and diastolic function than routine treatment group, the effect of long-term training needs to be confirmed by more researches.%目的:探讨康复运动对高血压病患者左室肥厚、舒张功能和血压的影响.方法:入选我院临床诊断为原发性高血压且合并左室肥厚(LVH)患者120例,采用随机数字表法随机均分为常规治疗组(60例,仅予常规降血压药物治疗)和康复运动组(60例,在常规降血压药物治疗基础上加康复运动).比较两组治疗后4周、8周、12周血压控制率,及治疗前和治疗12周后彩色多普勒超声心动图检测结果.结果:康复运动组在12周后血压的控制率明显高于常规治疗组(76.7%比58.3%,P=0.03).超声心电图显示两组患者治疗后左室舒张功能及左室肥厚各指标(除左室舒张末期内径外)均较治疗前有明显改善(P均<0.01),但两组治疗后比较均无显著性差异(P均>0.05).结论:康复运动训练能明显提高高血压病患者的血压控制率.中短期的运动训练未出现较常规治疗组显著改善左室肥厚和舒张功能的作用,长期训练的效果有待更多的研究证实.
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