首页> 外文期刊>中国癌症研究(英文版) >RELATIONSHIP AMONG PS2 PROTEIN EXPRESSION, ESTROGEN AND PROGESTERONE RECEPTOR STATUS, AND PROGNOSIS OF BREAST CANCER
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RELATIONSHIP AMONG PS2 PROTEIN EXPRESSION, ESTROGEN AND PROGESTERONE RECEPTOR STATUS, AND PROGNOSIS OF BREAST CANCER

机译:PS2蛋白表达,雌激素和孕酮受体状态与乳腺癌预后的关系

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摘要

Objective: To study the relationship between the expression of PS2 protein and Estrogen (ER) and Progesterone Receptor (PR) status and their prognotic value in breast cancer. Methods: Using the immunohistochemical method, PS2 protein expressions were detected in 105 cases with breast cancer. Results:The positive rate of PS2 protein was 50.48% (53/105) in 105 cases. The positive rate of PS2 in the patients who survived five years or more was 56.96% (45/79), which was higher than that of those who lived less than five years (30.77%, 8/26). In the ER, PR (+) patients, the positive rate of PS2 was higher (76.74%, 33/34), than that of those with ER, PR (-) (22.5%, 9/40). Conclusions:Our results suggest that the expression of PS2 protein was positively correlated with the S-year-survival and that of ER and PR in breast cancer. It is considered that PS2 may be as a prognostic predictor, and detection of PS2 protein expression was useful for a guiding treatment of breast cancer.
机译:目的:探讨PS2蛋白与雌激素(ER),孕激素受体(PR)的表达及其在乳腺癌中的预后价值。方法:采用免疫组织化学方法检测105例乳腺癌患者的PS2蛋白表达。结果:105例患者中PS2蛋白阳性率为50.48%(53/105)。存活5年以上的患者的PS2阳性率为56.96%(45/79),高于存活5年以下的患者(30.77%,8/26)。在ER,PR(+)患者中,PS2的阳性率更高(76.74%,33/34),比那些ER,PR(-)患者(22.5%,9/40)高。结论:我们的结果表明,乳腺癌中PS2蛋白的表达与S年生存率及ER和PR呈正相关。人们认为PS2可以作为预后预测指标,而PS2蛋白表达的检测可用于指导乳腺癌的治疗。

著录项

  • 来源
    《中国癌症研究(英文版)》 |1999年第4期|292-294|共3页
  • 作者单位

    Department of Pathology, Beijing Cancer Hospital, Beijing Medical University, Beijing 100036, China;

    Department of Pathology, Beijing Cancer Hospital, Beijing Medical University, Beijing 100036, China;

    Department of Biochemistry, Beijing Institute for Cancer Research, Beijing Medical University,Beijing 100034, China;

    Department of Pathology, Beijing Cancer Hospital, Beijing Medical University, Beijing 100036, China;

  • 收录信息 中国科学引文数据库(CSCD);
  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类 肿瘤学;
  • 关键词

    PS2 protein, ER, PR, Breast cancer,Prognosis;

    机译:PS2蛋白;ER;PR;乳腺癌;预后;
  • 入库时间 2022-08-19 03:43:16
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