LEEP联合银耳舒治疗宫颈癌前病变并发HPV感染的疗效分析

摘要

目的 分析宫颈环形电切术(Loop electrosurgical excision procedure,LEEP)治疗联合银耳舒对宫颈癌前病变并发高危型人乳头瘤病毒(human papillomavirus,HPV)感染的临床疗效.方法 选取2013年3月～2017年5月天津市北辰医院收治的88例宫颈癌前病变并发HPV感染患者作为研究对象,随机分为实验组与对照组各44例,对照组患者行LEEP治疗,实验组患者行LEEP联合银耳舒治疗.对比2组患者的HPV病毒载量,临床疗效与生活质量.结果 实验组患者的治愈率为95.45％明显高于对照组81.81％,差异有统计学意义(P<0.05),实验组患者的生活质量评分优于对照组,差异有统计学意义(P<0.05),实验组患者治疗后的HPV病毒载量低于对照组,差异有统计学意义(P<0.05).结论 LEEP治疗联合银耳舒对宫颈癌前病变并发HPV感染的临床疗效显著,可有效提升患者的生活质量,降低HPV病毒载量,值得临床推广应用.%Objective To analyze the clinical efficacy of LEEP combined with Tremella Shu in the treatment of cervical cancerous lesions complicated with high-risk human papillomavirus (HPV) infection. Methods From March 2013 to May 2017, 88 patients with cervical precancerous lesions complicated with HPV infection selected from March 2013 to May 2017 in Beichen Hospital of Tianjin were randomly divided into experimental group and control group,44 cases in each group. The control group were treated with LEEP, the experimental group was treated with LEEP combined with Tremella Shu,The HPV viral load, clinical efficacy and quality of life score were compared between the two groups. Results The cure rate was 95.45％ in the experimental group higher than that in the control group(81.81％),the difference was statistically significant (P<0.05). The quality of life score of the experimental group was better than that of the control group,the difference was statistically significant(P<0.05). The HPV viral load in the experimental group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion LEEP treatment combined with Tremella Shu on cervical precancerous lesions with HPV infection of clinical efficacy is significant, can effectively improve the quality of life of patients, reduce HPV viral load, worthy of clinical application.