Objective To investigate the clinical effect of milrinone in the treatment of children with congenital heart disease complicated by severe pneumonia and heart failure. Methods 94 patients with congenital heart disease complicated with severe pneumonia and heart failure in our hospital from March 2014 to February 2016 were selected,and randomly divided into experimental group and routine group,47 cases in each groups. The routine group were treated with conventional treatment, the experimental group in the conventional group received routine treatment based on the same given milrinone treatment. The clinical efficacy, symptom disappearance time and adverse reactions were compared between the two groups. Results The treatment in the experimental group the total efficiency (93.62%) was significantly higher than that of the conventional treatment group with the total effective rate (78.72%), significant difference, statistically significant (P<0.05); the experimental group in children with fever, cough, rales and other symptoms disappeared time is lower than the conventional group, the data had significant difference, has statistical significance (P<0.05); two groups of patients during treatment were not any serious adverse reactions, the adverse reaction condition no difference does not have statistical significance.Conclusion The clinical effect of milrinone in the treatment of children with congenital heart disease complicated by severe pneumonia and heart failure significantly, clinical efficacy, low incidence of adverse reactions, worthy of promotion.%目的 探讨米力农治疗小儿先天性心脏病并发重症肺炎及心力衰竭的临床应用效果.方法 选择2014年3月~2016年2月在义乌市中心医院接受治疗先天性心脏病并发重症肺炎及心力衰竭94例作为研究对象,将其分为实验组与常规组,各47例.常规组患儿采用常规治疗手段,实验组患儿在采用常规组相同的常规治疗基础上给予米力农进行治疗.对比2组患者的临床疗效、症状消失时间以及不良反应发生状况.结果 实验组患儿的治疗总有效率(93.62%)显著高于常规组患儿的治疗总有效率(78.72%),差异具有统计学意义(P<0.05);实验组患儿在发热,咳嗽、啰音等症状消失时间上低于常规组,各项数据差异具有统计学意义(P<0.05);2组患儿在治疗过程中均未发生任何严重不良反应,不良反应发生状况差异无统计学意义.结论 米力农治疗小儿先天性心脏病并发重症肺炎及心力衰竭的临床应用效果显著,临床疗效好,不良反应发生率低,值得推广.
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