首页> 中文期刊> 《中国生化药物杂志》 >视频脑电图结合MRI检查对药物难治性癫痫诊断的价值

视频脑电图结合MRI检查对药物难治性癫痫诊断的价值

         

摘要

目的 研究分析视频脑电图结合MRI检查对药物难治性癫痫诊断的价值.方法 选取本院2013~2015年收治的40例经确诊的药物难治性癫痫患者作为的研究对象.其中,26例患者为海马硬化,2例患者为颞叶萎缩伴脑发育不良,4例患者为脑灰质移位及巨脑回,3例患者为血管畸形,1例患者脑内囊肿,2例患者为胶质瘤,2例患者为外伤性癫痫.回顾分析本次选取的患者的临床资料,应用MRI扫描对痫灶区的表现特征进行体现,应用视频脑电图对发作间期痫样放电以及癫痫发病过程中的脑电活动情况和来源的部位进行分析,结合MRI扫描与视频脑电图结果,对照手术病理改变,分析结果,得出结论.结果 视频脑电图发作间期定位准确例数为21例,准确程度为52.5%,癫痫发作期的致痫灶来源定位准确例数为40例,准确程度为100.0%.MRI对发作间期的致痫灶及相关病变定位诊断准确例数为35例,准确率为87.5%,病变定性准确例数为30例,准确率为75.0%.结论 视频脑电图结合MRI检查对于药物难治性癫痫诊断有着十分重要的临床价值,能够对患者致痫灶的情况进行更加准确的诊断,为药物难治性癫痫患者的手术治疗提供信息,具有临床进一步推广和应用的意义.%Objective To study the value of video EEG combined with MRI in the diagnosis of intractable epilepsy.Methods40 patients with intractable epilepsy treated in our hospital from 2013 to 2015 were selected as the subjects.In 40 patients, 26 patients with hippocampal sclerosis, 2 cases of patients with temporal lobe atrophy with cerebral dysplasia, 4 cases of patients with cerebral gray matter and macrogyria, 3 cases of vascular malformation, 1 cases of patients with intracerebral cyst, 2 cases of patients with glioma, 2 cases of patients with traumatic epilepsy.Retrospective of The clinical data of the selected patients were analyzed and the manifestations of epileptic foci were reflected by MRI, The use of video EEG was used to detect the status and source of EEG during epileptic seizure and epilepsy Analysis, combined with MRI scan and video EEG results, control surgery pathological changes, analysis of the results, draw conclusions.ResultsThere were 21 cases of the accurate location of interictal EEG.The accuracy was 52.5%, and the accuracy of the location of epileptogenic foci was about 40, and the accuracy was about 100%.The accuracy of MRI in the diagnosis of epileptic foci and related lesions was 35 cases, the accuracy rate was 87.5%, and the number of lesions was qualitative and accurate in the case of 30 cases, with an accuracy rate of 75%.ConclusionVideo EEG combined with MRI examination for drug refractory epilepsy diagnosis has important clinical value, can make a more accurate diagnosis of patients with epileptogenic foci, provide information for surgical treatment of intractable epilepsy patients, with further clinical promotion and application significance.

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