This experiment was conducted to study the effects of adding β-hydroxy-β-methylbutyrate (HMB) to sow diets on reproductive performance of sows and growth performance of piglets and their immune function. Twenty crossbred pregnant sows (Landrace x Large White) were randomly allotted by parity and expected delivery date into 2 groups with 10 replicates of 1 sow. Control group was fed a basal diet, and experimental group was fed the basal diet supplemented with 2 000 mg/kg HMB. The experiment was from day 74 of gestation to day 21 after parturition. The results showed that with addition of 2 000 mg/kg HMB to late gestation and lactation sow diets, compared with the control group, birth weight of piglets born alive was increased by 14.1% (P<0.05), litter body weight at 7 and 21 days of age was increased by 16.6% andll.7% (P< 0. 05) , and litter body weight gain from birth to 7 days of age and from birth to 21 days of age was increased by 28. 3% and 12.5% (P < 0. 05). On day 98 of gestation and the day of parturition, compared with the control group, the serum immunoglobulin G (IgG) content of sows was increased by 35.3% (P <0. 01) and 13.0% ( P > 0. 05) , and the serum immunoglobulin M (IgM) content was increased by 34.7 % (P < 0.05) and 12.6% (P> 0.05). Compared with the control group, colostrum IgG content was increased by 19% (P <0. 05) , and milk IgM content on day 14 after parturition was increased by 21. 4% (P <0. 05). Compared with the control group, plasma IgG and IgM contents of piglets at 7 days of age were increased by 11.4% and 40. 1% (P< 0.05 ) . It is concluded that 2 000 mg/kg HMB can enhance body weight at birth and body weight gain during suckling periods of piglets, and improve immune function of sows and their suckling piglets. [Chinese Journal of Animal Nutrition, 2012, 24(9) : 1745-1753]%本试验旨在研究母猪饲粮添加β-羟基-β-甲基丁酸(HMB)对母猪繁殖性能及仔猪生长性能和免疫功能的影响.选取20头3～6胎次、妊娠74 d的“长×大”母猪,随机分成2组,每组10个重复,每个重复1头母猪,对照组饲喂基础饲粮,试验组在对照组基础饲粮中添加2 000 mg/kg HMB.试验从母猪妊娠第74天开始,至仔猪21日龄断奶结束.结果表明:与对照组相比,试验组仔猪初生个体重显著提高14.1％ (P ＜0.05),仔猪7、21日龄窝重分别显著提高16.6％、11.7％(P＜0.05),仔猪初生至7日龄、初生至21日龄窝增重分别显著提高28.3％和12.5％ (P ＜0.05)；与对照组相比,试验组母猪在妊娠第98天和分娩当天血清免疫球蛋白G(IgG)含量分别提高35.3％(P＜0.01)、13.0％(P＞0.05),免疫球蛋白M(IgM)含量分别提高34.7％ (P ＜0.05)、12.6％(P＞0.05)；与对照组相比,试验组母猪初乳中IgG含量显著提高19.0％ (P ＜0.05),分娩后第14天常乳中IgM含量显著提高21.4％(P＜0.05)；与对照组相比,试验组仔猪7日龄血浆IgG、IgM含量分别显著提高11.4％和40.1％ (P ＜0.05).上述结果提示,母猪妊娠后期及哺乳期饲粮中连续添加2 000 mg/kg HMB,可显著提高仔猪初生重和哺乳期增重,改善母猪及仔猪免疫功能.
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