巴贝斯虫感染对宿主红细胞及免疫系统的影响

摘要

巴贝斯虫（Babesia）是一种寄生于宿主红细胞的顶复门寄生虫，硬蜱为其传播媒介。由于巴贝斯虫感染后可以引起人或动物严重的临床症状，甚至造成死亡，给畜牧业和人类健康带来了极大威胁。本文主要综合国内外近年的研究成果，从巴贝斯虫入侵红细胞并对红细胞造成的影响，宿主感染后机体免疫状态的变化，以及共感染等方面进行综述，旨在为巴贝斯虫相关研究提供参考。%Babesia parasites are tick-transmitted intraerythrocytic protozoa of the phylum Apicomplexa, causing severe and even fatal disease and posing a great threaten for animal husbandry and human health. In this article, parasitic invasion to erythrocytes, changes of the host immune status after infection and aspects of co-infection are summarized according to the published results up to date. which will provide a reference for Babesia research.