卡泊三醇软膏联合糠酸莫米松软膏外用治疗神经性皮炎疗效观察

摘要

Objective To investigate the clinical effect of calcipotriol ointment combining with momestasone furoate ointment on neurodermatitis. Methods The 72 cases of neurodermatitis patients were randomly divided into two groups. The therapy group (35 cases) was treated topically with calcipotriol ointment combining with momestasone furoate ointment once daily. The control group (37cases) was topically using momestasone furoate ointment once daily.The treatment course lasted for 4 weeks. Results After four weeks, the total effective rate of treatment group was 82.9%,which was significantly higher than that of control group (51.4)with statistically significance ( P<0.01).The incidence of adverse reactions in treatment group and control group were 8.6% and 2.7%respectively.The difference wasn't statistically significant ( P>0.05). Conclusion Calcipotriol ointment combining with momestasone furoate ointment is effective and safe for the treatment of neurodermatitis.%目的：观察局部外用卡泊三醇软膏对神经性皮炎的临床疗效及其安全性。方法：将72例神经性皮炎患者随机分为两组。治疗组：35例，采用卡泊三醇软膏合并糠酸莫米松软膏局部外用治疗；对照组：37例，单独采用糠酸莫米松软膏治疗。均为每日1次，疗程为4周，观察比较两组间的有效率和不良反应发生率。结果：疗程结束后，治疗组患者的总有效率为82.9%，明显高于对照组的51.4%，差异有统计学意义（＜0.01）；治疗组不良反应发生率为8.6%，对照组为2.7%，两组间差异无统计学意义（＞0.05）。结论：卡泊三醇乳膏联合糠酸莫米松软膏治疗神经性皮炎安全、有效。