达英35联合2米诺地尔溶液治疗女性型脱发疗效观察

摘要

目的:观察达英35联合2%米诺地尔溶液治疗女性型脱发的临床疗效和安全性.方法:将110例女性型脱发患者随机分成两组.试验组:55例,采用达英35联合2%米诺地尔溶液治疗;对照组:55例,仅外用2%米诺地尔溶液治疗.两组治疗12周后评价疗效及不良反应.结果:治疗12周后,试验组有效率为70.91%,高于对照组的43.64%,两组间差异有统计学意义(P<0.05);睾酮及脱氢表雄酮水平显著低于对照组,差异具有统计学意义(P<0.05).两组间不良反应发生率比较无显著性差异(P>0.05).结论:达英35联合2%米诺地尔溶液治疗女性型脱发疗效优于单用2%米诺地尔,且安全性好.%ObjectiveTo observe the clinical efifcacy and safety of Diane-35(Ethinylestradiol and Cyproterone Acetate Tablets) and minoxidil in the treatment of female pattern hair loss.Methods 110 patients with female pattern hair loss were randomly divided into two groups: the experimental group was treated with Diane-35 and minoxidil, while the control group was treated with minoxidil only. The efifcacy and side effects was evaluated after treated 12-week treatment.Results After 12 weeks treatment, the total effective rates were 70.91% in the experiment group and 43.64% in the control group (P<0.05); the sera T and DHEA level of the experiment group Was signiifcantly lower than that of the control group (P<0.05); There were no signiifcant difference in side effective rate between two groups. ConclusionIt is effective and safe for Diane-35 in combination with minoxidil in the treatment of female pattern hair loss.