慢性乙型肝炎及其合并脂肪肝患者各级纤维化声触诊组织量化技术测值的对比研究

摘要

Objective:To investigate the effect of fatty liver on the measurement of virtual touch quantification (VTQ) in patients with hepatitis B. Methods:The VTQ value of 311 patients with chronic hepatitis B (study group) and another 311 patients with chronic hepatitis B combined with fatty liver (control group) were analyzed retrospectively. According to the classification of pathological liver fibrosis,two groups were grouped as S0,S1,S2,S3 and S4. The independent sample t-test of the mean VTQ value of two groups with the same level of fibrosis was conducted. Results:The patients with chronic hepatitis B had no grade S0. The VTQ values of S1～S4 level of study group had no significances with those of control group (all P>0.05). Conclusions:There was no significant difference in VTQ value of all levels of fibrosis in patients with chronic hepatitis B and chronic hep-atitis B with fatty liver.%目的:探讨脂肪肝对乙型肝炎(乙肝)患者声触诊量化技术(VTQ)测值的影响.方法:回顾性分析行肝穿刺活检的311例慢性乙肝患者VTQ值和311例慢性乙肝合并脂肪肝患者VTQ值.根据肝纤维化病理分级分别对上述2类患者分组(S0、S1、S2、S3、S4),并对其同级别纤维化的VTQ均值行独立样本t检验.结果:慢性乙肝患者无肝纤维化分级S0级,其S1～S4级的VTQ值与慢性乙肝合并脂肪肝相比差异均无统计学意义(均P>0.05).结论:慢性乙型肝炎与慢性乙型肝炎合并脂肪肝患者同级别纤维化VTQ值无明显差异.