Endothelial dysfunction in COVID-19 calls for immediate attention:the emerging roles of the endothelium in inflammation caused by SARS-CoV-2

摘要

The COVID-19 pandemic has caused numerous deaths around the world.A growing body of evidence points to the important role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation therapy against COVID-19 is emerging.In addition to affecting the lungs,COVID-19 can be a severe systemic inflammatory disease that is related to endothelial dysfunction.We are calling for closer attention to endothelial dysfunction in COVID-19 not only for fully revealing the pathogenic mechanism of COVID-19 but also for properly adjusting the strategy of clinical intervention.