白头翁皂苷D抗肿瘤的研究进展

摘要

Pulchinenoside D is the most widely and the highest titer monomer of many effective monomer components of Baitouweng in anti-tumor researches,which is one of the research hotspots of antitumor drugs in recent years.Pulchinenoside D inhibits tumor survival by inhibiting proliferation and promoting apoptosis of tumor cells,inhibiting energy metabolism,regulating autophagy and inhibiting tumor cell migration and metastasis.In this review,we collected related studies on anti-tumor of pulchinenoside D in recent years,which may provide new ideas for tumor treatment.%白头翁皂苷D是白头翁众多有效单体成分中在抗肿瘤方面研究最广泛、效价最高的单体,是近年来抗肿瘤药物研究的热点之一.白头翁皂苷D通过抑制肿瘤细胞增殖、促进肿瘤细胞凋亡、抑制能量代谢、调节自噬以及抑制肿瘤细胞迁移和转移等方面抑制肿瘤生存,现就近年来白头翁皂苷D抗肿瘤方面的相关研究进行综述.