Solid-Phase Stereoselective Synthesis of(E)-1,2-Disubstituted Ethenes from Polymer-Sopportedα-Selenoaldehydes

摘要

Reaction of polymer-supported α-selenoaldehydes with Grignard reagents affordedpolymer-bound β-hydroxyalkyl selenides, which treated with thionyl chloride and triethylamineleading to (E)-1, 2-disubstituted ethenes in good yield.