A Convenient Method for Synthesis of Novel Cyclic Ethers (1R, 2R,3R, 5S, 7S, 9R, 12R)-3-(t-Butyldimethylsilyl)oxy-7-methoxymethyloxy-2, 10-dimethyl-12-oxatricyclo 7.2.1.05,12 dodecane

摘要

Novel cyclic esters (1R, 2R, 3R, 5S, 7S, 9R, 12R)-3-(t-butyldimethylsilyl)oxy-7-methoxymethyloxy-2, 10-dimethyl-12-oxatricyclo [7.2.1.05,12] dodecane were prepared when their precursor 1 was treated with SOCl2/pyridine. A plausible mechanism was hypothesized.