A highly flexible green synthesis of 1H-pyrazolo1,2-bphthalazine-5,10-dione derivatives with CuI nanoparticles as catalyst under solvent-free conditions

摘要

CuI nanoparticles as an efficient catalyst have been used for the preparation of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones by the four-component condensation reaction of phthalic anhydride, hydrazine monohydrate, aromatic aldehydes and malononitrile or ethyl cyanoacetate under solventfree conditions in good to excellent yields, short reaction times and environmentally benign, milder reaction conditions.