Catechin compounds is one kind of polyphenol antioxidant that possess a great physiological aetivties. In this paper, progress of lipid-soluble catechins' preparation that use molecules modification were reviewed. Chemical method is mainly using carbonyl chlorides and catechin compounds in reaction under the role of chemical catalyst to prepare lipid-soluble catechins. But acylation reaction happened at different locus. The carbon chain length of acyl donors generally is more than 8. Enzymatic modification is mainly using fatty acid or fatty acid ester with catechins under the role of lipase, then direct esterification or ester exchange happened to get lipid-soluble catechins. Alkyl is bonded in catchin compounds, thus solubility in oil system of the catechin compounds is raising, and expand the application fields.%儿茶素类化合物是一类具有多种生理活性的多酚类抗氧化剂.本文综述了国内外利用分子修饰法制备脂溶性儿茶素类化合物的进展。化学法主要利用酰氯在化学催化剂作用下反应制备脂溶性儿茶素.但是酰化反应发生的位点有所不同.总的来说酰基供体碳链长度一般大于等于8;酶法主要利用脂肪酶使脂肪酸或脂肪酸酯通过直接酯化或酯交换反应制备脂溶性儿茶素.在儿茶素及其化合物上键合烷基.由此提高了儿茶素类化合物在油脂体系中的溶解度,拓展了其应用领域。
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