目的：研究单胎孕妇与多胎孕妇血浆D-二聚体水平差异。方法正常妊娠产妇1089名,其中977名单胎孕妇,112名多胎孕妇,调查其D-二聚体水平和个人信息,并进行统计分析。结果无论在单胎还是多胎孕妇中D-二聚体水平与妊娠周数均呈正相关性。单胎孕妇和多胎孕妇血浆D-二聚体水平,在妊娠前期单胎孕妇(96±29)ng/ml,多胎孕妇(118±24)ng/ml,差异无统计学意义(P>0.05)；在妊娠中期单胎孕妇(230±31)ng/ml,多胎孕妇(238±37)ng/ml和后期单胎孕妇(362±29)ng/ml,多胎孕妇(394±35)ng/ml,差异有统计学意义(P<0.05)。结论多胎孕妇血浆D-二聚体水平比单胎孕妇明显增高。%Objective To study the differences of the D-dimer levels between women with singleton and multifetal pregnancies. Methods D-dimer levels and personal information of 1,089 pregnant women were surveyed and analyzed. Among those women, there were 977 singleton pregnancies and 112 multifetal pregnancies. Results The D-dimer levels were significantly and positively correlated with gestational week in all women with singleton or multifetal pregnancies. The D-dimer levels determined at the first trimester did not differ significantly (P>0.05), which was (96±29)ng/ml for singleton pregnancy and (118±24)ng/ml for multifetal pregnancy. The levels at the second trimester, (230±31)ng/ml for singleton pregnancy and (238±37)ng/ml for multifetal pregnancy, and the third trimester (362±29)ng/ml for singleton pregnancy and (394±35)ng/ml for multifetal pregnancy, were statistically significant in their differences (P<0.05). Conclusion The degree of D-dimer in multifetal pregnancy is higher than that of singleton pregnancy.
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