基于指南评估我院治疗耐甲氧西林金黄色葡萄球菌感染的抗菌药物应用

摘要

OBJECTIVE:To investigate the use of antibiotics for Methicillin-resistant Staphylococcus aureus (MRSA) infection in our hospital,and to analyze the cause of anti-infection failure.METHODS:The data of patients receiving anti-infection treatment of MRSA were collected from our hospital in 2011.Therapeutic efficacy was evaluated in terms of basic situation of patients,infection site,susceptibility data,varieties,dose and course of anti-infection agents based on IDSA GUIDE in 2011 and the Same Minds of Experts in China.RESULTS:The treatment regimen of MRSA in our hospital corresponded with guideline mainly,but there were some problems about drug selection and drug dosage.CONCLUSIONS:Clinical pharmacists must play a role on treatment of MRSA infection to improve cure rate.%目的:调查我院治疗耐甲氧西林金黄色葡萄球菌(MRSA)感染的抗菌药物使用情况,分析导致抗感染失败的原因.方法:收集2011年在我院进行抗MRSA感染治疗的患者资料,在美国感染性疾病学会2011年发布的《耐甲氧西林金黄色葡萄球菌感染的循证治疗指南》以及我国《耐甲氧西林金黄色葡萄球菌感染防治专家共识》的基础上,从患者的基本情况、感染部位、药敏数据与选用的抗感染药物的品种、剂量、疗程等方面对治疗效果进行评价.结果:我院MRSA感染的治疗方案与指南的推荐基本相符,但仍存在选药不当与用药剂量过小的问题.结论:应充分发挥临床药师的作用,为抗MRSA感染提供服务,提高MRSA感染的治愈率.