雷贝拉唑联合奥美拉唑治疗幽门螺杆菌感染性消化性溃疡临床评价

摘要

目的：探讨雷贝拉唑联合奥美拉唑治疗幽门螺杆菌（HP）感染性消化性溃疡的临床疗效。方法选取医院2014年至2015年HP感染性消化性溃疡患者50例，随机分为试验组和对照组，各25例，对照组患者用雷贝拉唑治疗，试验组患者用雷贝拉唑联合奥美拉唑治疗。观察并比较两组患者的临床疗效、不良反应、住院时间和医疗费用。结果试验组患者的临床有效率为72.00%，明显高于对照组的44.00%（ P0.05），试验组患者的住院时间及住院费用均较对照组少，差异有统计学意义（ P 0. 05),but the hospitalization time and hospital costs of the experi-mental group were significantly less than the control group( P < 0. 05). Conclusion Rabeprazole combined with omeprazole in treating peptic ulcer patients infected helicobacter pylori can improve the clinical efficacy,reduce the gastric acidity and protect gastric mucosa, which is worthy of clinical application.