Objective To study the clinical effect of primary hyperhidrosis of hand, foot treated with T3-4 thoracoscopic sympathectomy. Methods 93 cases of hand, foot hyperhidrosis patients were selected from January 2014 to November 2014 in our hospital, T3-4 group had 46 patients, T3 group had 47 cases. The postoperative compensatory hyperhidrosis cases, plantar more Khan remission, quality of life improvement of two groups were compared. Results There were 15 patients with compensatory hyperhidrosis, there were no significant difference between T3-4 group and T3 group in the light - moderate sweating incidence(P > 0.05). The plantar hyperhidrosis efficiency of T3-4 group was higher than T3 group, the difference was statistically significant (P < 0.05).The iQOL score of T3-4 group and T3 group after operation were significantly lower than before operation, T3-4 group was significantly lower than T3 group, the difference was statistically significant (P < 0.05). Conclusion The efficacy of primary hyperhidrosis patients with hand, foot treated with T3-4 thoracoscopic sympathectomy is better, which can effectively alleviate or eliminate the clinical symptoms, safe, especially for the combined plantar hyperhidrosis hyperhidrosis patients.%目的：探讨胸腔镜下T3～4交感神经干切断术治疗原发性手足多汗症的临床效果。方法2014年1～11月我院共收治手足多汗症患者93例，T3～4组46例，T3组47例，比较两组患者术后代偿性多汗情况、足底多汗缓解情况、生活质量改善情况。结果共有15例患者出现代偿性多汗，T3～4组、T3组轻-中度多汗发生率差异无统计学意义（P ＞0.05）。T3～4组足底多汗有效率与 T3组比较高，差异有统计学意义（ P ＜0.05）。术后T3～4组及T3组iQOL评分与术前比较均出现明显降低，T3～4组术后iQOL评分明显低于T3组，两组差异有统计学意义（P＜0.05）。结论原发性手足多汗症患者采用胸腔镜下T3～4交感神经干切断术治疗疗效确切，可有效缓解或消除患者临床症状，安全性高，尤其适用于合并足底多汗的手汗症患者。
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