首页> 中文期刊> 《中国医药科学》 >孟鲁司特钠与氯雷他定联合糠酸莫米松鼻喷剂治疗过敏性鼻炎合并轻中度腺样体肥大临床分析

孟鲁司特钠与氯雷他定联合糠酸莫米松鼻喷剂治疗过敏性鼻炎合并轻中度腺样体肥大临床分析

         

摘要

Objective To compare the clinical effect and relapse rate of different dosing regimens for allergic rhinitis(AR) and adenoidal hypertrophy (AH). Methods 142 patients with allergic rhinitis(AR) and adenoidal hypertrophy (AH) in our hospital were divided into group A,group B and group C, according to different treatment strategies.The clinical effect of these 3 groups were compared. Results After 1 month of medication, there was small difference in the data of total effects of AR and AH in first 2 groups (P>0.05).But there was significant difference in group C and the first 2 groups in the data of AR and AH (P<0.05)After one month’s treatment, compared with before treatment, there was significant difference in sleep disorder index scores and A/N of group C than those of the first 2 groups (P<0.05).3 months after stop taking medication,the first 2 groups were more likely to relapse (P<0.05). Conclusion Combined clinical application of 3 drugs in the treatment of allergic rhinitis(AR)and Light-medium adenoidal hypertrophy (AH) has notable curative effects and uneasy relapse, and it has significant clinical promotion value.%目的:对比不同给药方案治疗AR合并轻中度AH的临床疗效与复发率。方法将我院收治的142例AR合并轻中度AH患儿依据不同治疗方案分组,对比组间疗效。结果用药1个月后,前两组AR与AH的总疗效其数据差异无统计学意义(P>0.05);而C组此两项与前两组比较后发现各项数据差异有统计学意义(P<0.05);治疗1个月后三组间与治疗前对比、C组与A、B两组治疗后睡眠障碍症状指标评分与A/N对比差异有统计学意义(P<0.05);前两组停药3个月后更易引起复发(P<0.05)。结论临床予以AR合并轻中度AH患儿三种药物联合应用的治疗方案,具显著疗效且更不易复发,该法深具临床推广价值。

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