中西医结合疗法对妊娠期肝内胆汁淤积综合征患者的影响分析

摘要

Objective To study the therapeutic effect of integrated traditional Chinese and Western medicine therapy in treatment of intrahepatic cholestasis of pregnancy. Methods 81 cases of patients with intrahepatic cholestasis of pregnancy cured in our hospital from January 2013 to January 2015 were selected and randomly divided into two groups according to number table method.41 cases were divided into control group and treated with western medicine,and 40 cases were divided into observation group and treated with western medicine,using a combination of traditional Chinese medicine decoction.Curative effect and adverse reaction of patients in the two groups were observed and compared. Results There were no significant differences on serum total bile acid and alanine aminotransferase level between the two groups before the treatment.After treatment,serum total bile acid and alanine aminotransferase level of observation group were significantly lower than those of control group,the differences were statistically significant(P < 0.05).The effective rate of the observation group was significantly higher than that of the control group,differences were statistically significant(P < 0.05)).The number of vaginal delivery of observation was significantly more than that of control group,but the complication related to the number of cases was significantly less than that of control group,and the difference was statistically significant(P < 0.05). Conclusion The combination of traditional Chinese and Western medicine treatment can effectively improve the symptoms of intrahepatic cholestasis of pregnancy in pregnant women.It is conducive to pregnant women's pregnancy outcome.It is worth promoting the application.%目的：研究中西医结合疗法对妊娠期肝内胆汁淤积综合征患者的疗效情况。方法选取2013年1月～2015年1月于我院接受治疗的妊娠期肝内胆汁淤积综合征患者81例，按数字表法将患者随机分为两组，其中对照组41例，单纯使用西医药物对患者进行治疗，观察组40例，在对照组西医治疗的基础上，联合使用中药汤剂对患者进行治疗，观察并对比两组患者治疗效果以及不良反应等情况。结果治疗前两组患者血清总胆汁酸以及谷丙转氨酶的水平无统计学意义，治疗后观察组均显著低于对照组，差异有统计学意义（P ＜0.05）；就两组患者治疗有效率而言，观察组要显著高于对照组，且阴道分娩的例数也显著对于对照组，但并发症情况观察组则显著少于对照组，差异有统计学意义（P ＜0.05）。结论中西医结合治疗能有效改善孕妇在妊娠期肝内胆汁淤积的症状，有利于孕妇的妊娠结局，值得推广应用。