辅助生殖技术受孕双胎与自然受孕双胎的产前超声筛查结果及胎儿的健康状况比较观察

摘要

Objective To compare the prenatal ultrasound screening results and fetal health status of twin pregnancy and twin pregnancy in assisted reproductive technology (ART). Methods 90 cases of pregnant women with twin pregnancy after ART from January 2011 to June 2015 were selected as observation group, 100 cases of spontaneous twin pregnant women were selected as control group. The relevant data of prenatal ultrasound examination and fetal situation were collected, and pregnancy outcome of the two groups were compared. Results Polyhydramnios, umbilical cord around the neck, the incidence of premature rupture of membranes rate, placenta previa incidence, anemia rate and postpartum hemorrhage incidence of the two groups had no significant difference (P < 0.05). The average amount of amniotic fluid of observation group was significantly more than that in control group. Amniotic fluid, umbilical cord attachment position change incidence of observation group were significantly lower than those of control group (P<0.05). The rate of fetal malformation, stillbirth rate of two groups had no significant difference (P>0.05). Twin transfusion syndrome incidence of observation group was significantly lower than that of control group (P<0.05). In the two groups, the number of live births, congenital malformations, average gestational age, low birth weight infants and neonatal asphyxia were not significantly different (P > 0.05). The average body weight of observation group was significantly higher than that of control group (P <0.05). Conclusion ART twin pregnancy does not increase the risk of perinatal complications. Compared to natural pregnancy, it has obvious advantages on amniotic fluid abnormalities, changes in the umbilical cord and the twin transfusion syndrome.%目的：比较辅助生殖技术受孕双胎与自然受孕双胎的产前超声筛查结果及胎儿的健康状况。方法选取2011年1月～2015年6月期间在我院应用辅助生殖技术（ART）怀孕双胎90例孕妇设为观察组，及同期自然受孕双胎100例孕妇为参照组，收集产前超声检测得到的相关数据以及胎儿情况，对比分析并比较两组的妊娠结局。结果两组在羊水过多、脐带绕颈发生率、胎膜早破发生率、前置胎盘发生率、贫血发生率和产后出血发生率等方面比较无显著差异（P＜0.05）；观察组平均羊水量显著多于参照组，羊水过少、脐带附着位置变化发生率显著低于参照组（P＜0.05）。两组患者胎儿畸形率、死胎率无显著差异（P＞0.05）；观察组双胎输血征发生率显著低于参照组（P＜0.05）。两组在活婴数、先天畸形、平均胎龄、低体重儿必理、新生儿窒息比例等方面差异不显著（P＞0.05）；观察组胎儿平均体重显著高于参照组（P＜0.05）。结论ART双胎受孕未增加围产期孕妇并发症发生风险，与自然受孕相比在羊水异常、脐带位置变化及双胎输血综合征方面具有明显优势。