目的 研究番泻叶、果导加西沙必利和开塞露解除卧床患者便秘的效果.方法 将入选病例按贯序法分成番泻叶组(60例)、果导+西沙必利片组(60例)和开塞露组(60例).观察三组患者用药后12 h内大便排出率、第一次排便时间、排便次数、大便性状、大便量,以及排便时患者的血压数值和有无直肠出血等不良反应.结果 三组患者12 h内大便排出率、第一次排便时间、排便次数、大便性状、大便量、患者接受程度等方面比较,差异有统计学意义(P<0.01、P<0.05).三组患者排便时的血压、有无直肠出血等不良反应比较差异无统计学意义(P>0.05).结论 三种泻药解除卧床患者便秘安全有效,各有优缺点,口服番泻叶浸泡液和开塞露灌肠解除卧床患者便秘的效果优于果导加西沙必利.%Objective To study the effect of Senna, Phenolphthalein combined with Cisapride and Glycerine Enema in the treatment of bedridden patients with constipation. Methods According to the sequential method, selected cases were divided into Senna group (60 cases), Phenolphthalein combined with Cisapride group (60 cases) and Glycerine Enema group (60 cases). Stool discharge rate within 12 hours after treatment, first defecation time, defecation frequency, character and weight of stool, blood pressure when defecating, adverse reactions such as hemoproetia, patient acceptance level of all patients In three groups were observed- Results Stool discharge rate within 12 hours .after treatment, first defecation time, defecation frequency, character and weight of stool and patient acceptance level of three groups patients showed statistically significant difference (P ＜ 0.01, P ＜ 0.05). While blood pressure when defecating, adverse reactions such as hemoproctia of three groups patients were not statistically significant (P ＞ 0.05). Conclusion The three kinds of laxatives are safe and effective to relieve constipation of bedridden patients, and there are advantages and disadvantages to each laxative. The effect of senna immersion fluid taken orally and glycerine enema clystered is better than phenolphthalein combined with cisapride.
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