自体碎骨联合Bio-OSS骨粉应用于颌骨囊肿术后骨缺损中的临床效果

摘要

目的 探讨自体碎骨联合Bio-OSS骨粉在颌骨囊肿术后骨缺损患者中的临床效果.方法 选取2014年3月～2015年12月湖北医药学院附属人民医院口腔科收治的颌骨囊肿术后骨缺损患者60例,按随机数字法分为对照组(30例)和观察组(30例).对照组采用Bio-OSS骨粉治疗,观察组在对照组基础上联合自体碎骨治疗,于术前及术后不同时间点利用CT进行检查,计算植骨区CT值及差值,比较两组临床疗效及切口愈合情况.结果 观察组手术后切口愈合率优于对照组(P＜0.05).观察组术后3、6、9个月CT值均高于对照组(P＜0.05).观察组术后3、6、9个月差值水平均低于对照组(P＜0.05).结论 将自体碎骨联合Bio-OSS骨粉用于颌骨囊肿术后骨缺损中的效果理想,该方法有助于切口愈合,改善植骨区CT值及差值,值得推广应用.%Objective To investigate the clinical effect of autologous bone graft combined with Bio-OSS bone meal in patients with bone defect after jaw cyst.Methods From March 2014 to December 2015,60 patients with jaw cysts treated in the Department of Stomatology,the People's Hospital Affiliated to Hubei Medical College were divided into control group (30 cases) and observation group (30 cases) by random number table.The control group was treated with Bio-OSS bone meal.The observation group was treated with autologous bone grafting on the basis of the control group.CT examination was performed at different time points before and after operation.The CT values and difference values in bone graft area were calculated,and the clinical efficacy and incision healing were compared.Results The healing rate in the observation group was better than that in the control group (P ＜ 0.05).The CT values of the observation group were higher than those of the control group at 3,6 and 9 months after operation (P ＜ 0.05).The difference values of the observation group werre lower than those of the control group at 3,6 and 9 months after operation (P ＜ 0.05).Conclusion Autologous bone graft combined with Bio-OSS bone meal is effective in the postoperative bone defect of jaw cysts,which is helpful for incision healing and improving the CT value and difference value.It is worthy to be popularized.