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一种基于脑电图的大脑可塑性研究

             

摘要

本文设计了一套手指按键运动测试系统,对19位健康被试者分别采集了安静状态下和测试-训练-测试-训练-测试5个模块下的实验数据.手指按键运动实验中,运动测试模块含有可对学习训练效果进行评价的参数,本文使用统计学的方差分析法对实验获取数据进行了研究分析,结果表明训练对运动测试结果有显著影响;使用相关性分析对大脑运动皮层的连通性进行研究,发现通过训练,在大脑运动区中超过80%的连结都得到了增强,尤其是C4电极所在位置的脑区,C4信号与其他所有电极信号的相关性都得到了增强.信号之间相关的增强与脑区之间联系的增强以及运动能力的提高有很明显的相关性.通过脑电图实验的研究分析结果,本文认为在运动训练的作用下,大脑的相关脑区之间的连通性提高了运动成绩,即大脑发生了可塑性变化.%Cerebral plasticity is an important branch of brain science. Motor cortex infraction like stroke may cause subsequent movement disorders or even disability. To investigate the plasticity of cerebral MCN (motor cortex network) can not only reveal the essence of learning, give objective opinion of learning process, but also help doctors with scientific rehabilitation schedule.Nineteen healthy adults, who seldom played musical instruments or keyboards, were included in the EEC test. Specific finger movement training was performed. The task comprised sessions of rest- test- train- test- train -test. Thirty-six channel EEG signals were recorded in different test sessions prior to and after training. Data were statistically analyzed using one-way analysis of variance. Motor function of all subjects was significantly improved in the third test compared with the first test More than 80% of connections were strengthened in the motor-related areas following two training sessions, in particular the primary motor regions under the C4 electrode. These results provided a greater understanding of the mechanisms involved in motor cortex network.The results of EEC test suggest that training improved motor function. Motor related cortex connectivity was increased which reflect the plasticity of motor cortex.

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