32例急性心肌炎短暂心室壁增厚患者临床分析

摘要

目的：回顾性分析病毒性心肌炎短暂心室壁增厚患者临床特点及预后。方法收集该院2006年11月-2013年11月期间收治的126例成人病毒性心肌炎患者，分析其中32例表现为室壁增厚的患者临床资料，并比较治疗前后患者心超学指标的变化。结果患者入：与出：时的室间隔厚度(IVST)分别为(12.7±2.49)mm和(10.33±1.21)mm(P=0.000)；左室后壁厚度(LVPWT)分别为(11.93±3.6)mm和(9.85±1.1)mm(P=0.004)；左室舒张末期内径(LVDD)分别为(48.67±5.88)mm和(51.19±4.51) mm(P=0.029)；左室射血分数(LVEF)分别为(0.46±0.09)和(0.59±0.11)(P=0.000)。治疗后患者的临床症状得到显著性改善，且与治疗前差异有统计学意义(P<0.05)。结论表现为短暂室壁增厚的急性心肌炎患者经积极治疗后，心肌增厚可消退。%Objective To analyze the clinical manifestations and prognosis of acute viral myocarditis with transient ventricular wall thickening retrospectively. Methods 126 adult patients with viral myocarditis admitted in our hospital from November 2006 to November 2013 were collected, of them, the clinical data of 32 patients with ventricular wall thickening were analyzed. And the changes of echocardiography indexes of the patients before and after treatment were compared. Results The IVST was 12.7±2.49mm when admitted and 10.33±1.21mm when discharged (P=0.000), the LVPWT was 11.93±3.6 mm when admitted and 9.85±1.1mm when discharged (P=0.004). The left ventricular end-diastolic diameter (LVDD) was 48.67±5.88mm when admitted and 51.19±4.51 mm when discharged (P=0.029). The left ventricular ejection fraction (LVEF) was 0.46±0.09 when admitted and 0.59±0.11 when discharged (P=0.000). The clinical manifestations of the patients improved after the treatment, and compared with those before treatment, the difference was statistically significant (P<0.05). Conclusion For some patients with acute myocarditis and transient ventricular wall thickening, the myocardial thickening can be dissipated after active treatment.