目的：探讨依托咪酯静脉不同速度输注对胸科手术患者麻醉诱导期肌阵挛的影响。方法资料选取2012年1月-2013年3月该院收治的行胸科手术的男性患者105例，将其平均分为3组，在麻醉诱导期以不同速度静注依托咪酯0．3 mg/kg。结果3组患者在即刻注药、注药停止以及停止后2 min的心率及经皮脉搏氧饱和度的组间及组内比较，差异无统计学意义。但在停止注药及停止后2 min的血压比较，V400组、V800组明显小于V200组，差异有统计学意义(P＜0.05)。3组患肌阵挛的发生率及肌阵挛程度比较，V200组低于V400组、V800组，V400组低于V800组差异有统计学意义(P＜0.05)。结论依托眯酯输注速度减缓,可降低胸科手术患者麻醉诱导期肌阵挛的发生率及肌阵挛程度。%Objective To study the impact of intravenous infusion of Etomidate at different speeds on the myoclonus of patients with thoracic surgery during the anesthesia induction period. Methods The data of 105 cases of male patients underwent thoracic surgery in our hospital from January, 2012 to March, 2013 were selected and divided into 3 groups equally, and given intravenous infusion of Etomidate 0.3 mg/kg at different speeds during the anesthesia induction period. Results There were no statistically sig-nificant differences in heart rate, percutaneous pulse oxygen saturation between the 3 groups or within the group at the time of im-mediate infusion of drug, stopping infusion of drug, and 2 minutes after the stopping infusion of drug, but comparing the blood pressure at the time of stopping infusion of drug, and 2 minutes after the stopping infusion of drug, the blood pressure of V400 group and V800 group were much lower than that of V200 group, the difference was statistically significant (P<0.05). The inci-dence and the severity of myoclonus of V200 group were lower than those of V400 group and V800 group, and those of V400 group were lower than those of V800 group, the differences were statistically significant(P<0.05). Conclusion Slower infusion of E-tomidate can reduce the incidence and severity of myoclonus of patients with thoracic surgery during the period of anesthesia induction.
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