冠心病合并抑郁症患者血清中血管内皮生长因子与抑郁症严重程度的关系

摘要

目的：探讨冠心病合并抑郁症患者血清中血管内皮生长因子（VEGF）与抑郁症严重程度的关系。方法比较健康体检者、冠心病患者和冠心病合并抑郁症患者血清中VEGF的表达，比较不同抑郁程度冠心病患者血清中VEGF的水平。结果健康体检者、冠心病患者和冠心病合并抑郁症患者血清中VEGF存在的差异有统计学意义（P＜0.05）；且不同抑郁程度冠心病患者血清中VEGF的水平亦存在显著差异（P＜0.05）。结论 VEGF与冠心病合并抑郁症患者抑郁症严重程度存在一定关系。%Objective To investigate depression in patients with coronary heart disease and vascular endothelial growth factor (VEGF) the relationship between depression severity.Methods Comparison of different levels of depression in patients with coronary heart disease in serum VEGF levels. Results Health examination, in patients with coronary heart disease and coronary heart disease in patients with depression in VEGF has signiifcant difference (P<0.05), and the level of vascular endothelial growth factor VEGF in different degree of depression in patients with coronary heart disease also has signiifcant difference (P<0.05).Conclusion VEGF in patients with coronary heart disease and depression negatively correlated with the severity of depression.