从牛肺提取精品肝素钠工艺的研究

摘要

本文报道了酶解盐解、D-254树脂吸附、沉淀剂YNB99-1去蛋白和H2O2氧化制取牛肺精品肝素钠的工艺。结果显示，精品效价150USPu/mg、质量符合出口标准，产率比传统工艺提高22.6%；下脚料-肺渣可用以制取饲料蛋白。%A new techniques of exacting heparin sodium from bovine lung is presented in this article. This technics includes digesting bovine lung with proteolysis enzyme and sodium chloride, extracting heparin sodium with D-254, removing protein with YNB-99-1 and oxidizating with H2O2. The effective value of the product from this technics reaches 150USPu/mg, which is fit to the exporting standards. The product percentage of this thchnics is higher than that of traditional technics by 22.6% and the final residual bovine lung from this thchnics can be used as feed protein.