Nine hydronopol quaternary ammonium salts (hydronopol dimethyl alkyl ammonium halide) , which were hydronopol dimethyl ethyl ammonium bromide (2 a) , hydronopol dimethyl n-propyl ammonium bromide (2 b) , hydronopol dimethyl n-butyl ammonium bromide (2 c) , hydronopol dimethyl n-pentyl ammonium bromide (2 d) , hydronopol dimethyl benzyl ammonium bromide (2 e) , hydronopol dimethyl benzyl ammonium chloride (2 f) , hydronopol dimethyl ethyl ammonium iodide (2 g) , hydronopol dimethyl n-propyl ammonium iodide (2 h) , and hydronopol dimethyl n-butyl ammonium iodide (2 i) , were synthesized by the reaction of hydronopol dimethyl amine and 9 halogenated hydrocarbons, respectively. The identification and structural analysis were carried out by using FT-IR, MS and NMR methods, and the inhibition effects of the nine compounds on eight plant pathogens were tested by the method of mycelium growth rate method. The results showed that under the concentration of 500 mg/L, 9 compounds had certain inhibitory effects on the 8 plant pathogenic fungi, among which the bacteriostatic performance of 2 d were the best, the bacteriostatic rates against Fusarium proliferatum, Alternaria kikuchiana, Sclerotinia sclerotiorum, Ceratosphaeria phyllostachydis, and Sphaeropsis sapinea reached 100％, and 2 b, 2 c and 2 f also had excellent results, the bacteriostatic rate reached 100％.%由氢化诺卜基二甲基胺与9种卤代烃反应制得含氢化诺卜基的季铵盐化合物 (氢化诺卜基二甲基烷基卤化铵) , 分别为氢化诺卜基二甲基乙基溴化铵 (2a) 、氢化诺卜基二甲基正丙基溴化铵 (2b) 、氢化诺卜基二甲基正丁基溴化铵 (2c) 、氢化诺卜基二甲基正戊基溴化铵 (2d) 、氢化诺卜基二甲基苄基溴化铵 (2e) 、氢化诺卜基二甲基苄基氯化铵 (2f) 、氢化诺卜基二甲基乙基碘化铵 (2g) 、氢化诺卜基二甲基正丙基碘化铵 (2h) 、氢化诺卜基二甲基正丁基碘化铵 (2i) .采用红外光谱和核磁共振表征了它们的结构, 并用菌丝生长速率法测试了9种化合物对8种植物病原真菌的抑制效果, 结果表明:在药液质量浓度为500 mg/L下, 9种化合物对8种供试病原菌均具有一定的抑制效果, 其中2d的抑菌效果最好, 对层出镰刀菌、梨链格孢菌、辣椒菌核病菌、毛竹枯梢病菌、松枯梢病菌的抑菌率均达到100％, 2b、2c和2f也具有优异的抑菌性能, 对辣椒菌核病菌的抑菌率均达到100％.
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