采用小鼠耳肿胀法对滇白珠种子75%乙醇提取物的石油醚、氯仿、乙酸乙酯、正丁醇萃取物和水溶部分的抗炎效果进行测试。结果表明乙酸乙酯萃取物能显著减轻二甲苯致炎小鼠的耳廓肿胀度。采用色谱技术分离抗炎效果较好的乙酸乙酯萃取物的化学成分,得到8个化合物。通过NMR、IR、MS等波谱法鉴定,8个化合物为：大黄素甲醚(1)、6-乙基-5-羟基-2,7-二甲氧基-1,4-萘醌(2)、杨梅素(3)、对苯二酚(4)、香草酸(5)、β-胡萝卜苷(6)、β-谷甾醇(7)和丁二酸(8)。以上所有化合物都为首次从滇白珠种子中分离得到。%The extract parts of Gaultheria yunnanensis seeds, which were extracted with petroleum ether, chloroform, ethyl acetate, butanol, and water from 75% ethanol extract, were investigated through pharmacological experiments. The ethyl acetate extract was the antiphlogistic part. Through the use of chromatographic technology, eight compounds were isolated from the antiphlogistic part. Their structures were identified by spectroscopic analyses, such as NMR, IR and MS, etc. . They were physcion (1), 6-ethyl-5-hydroxy-2,7-dimethoxy-1,4-naphthoquinone (2), myricetin (3), 1,4-dihydroxybenzene (4), vanillic acid (5),β-daucosterol (6),β-sitosterol (7) and succinic acid (8). All compounds were isolated from the plant seeds for the first time.
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