双亲性羧甲基壳聚糖钠盐席夫碱衍生物的合成及其性能研究

摘要

旨在以天然产物为基础,设计与合成具有表面活性和抗菌等特性的多功能高分子,拓宽天然产物应用领域.首先壳聚糖与一氯乙酸取代反应获得O-羧甲基壳聚糖钠盐,然后依次与柠檬醛、对羟基苯甲醛进行席夫碱反应,最终制得O-羧甲基壳聚糖钠盐缩柠檬醛缩对羟基苯甲醛,并通过1 H-NMR和元素分析对产物的结构进行表征.通过测定终产物的表面张力(γ)、临界胶束浓度(CMC)、亲水亲油平衡值(HLB)、乳化能力和抗菌能力等对其性能进行评价,结果表明:该产物具备表面活性且其水溶液能够抑制细菌增长,具有成为功能性高分子表面活性剂的潜力.%Schiff's base of carboxymethyl chitosan sodium was synthesized by the reaction of carboxym-ethyl chitosan sodium with citral and p-hydroxy benzaldehyde successively. The structure of these Schiff's base derivatives were characterized by 1 H NMR and EA. It showed that the amino groups in carboxymethyl chitosan were reacted with citral and p-hydroxy benzaldehyde to form the Schiff's base derivatives. The HLB value, surface tension, emulsifying ability and antibacterial properties of the products were also investigated. The results showed that these water-soluble products have potential as polymeric surfactant with macromolecular antimicrobial.