Syntheses and Biological Activities of Novel Benzotriazole Compounds Containing a Thioamide Group

摘要

(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-3-(4-chlorophenyl)-3-hydroxy-N-phenylprop-2-enethioamide(compound 1) and(E)-2-(1H-benzo[d][1,2,3]triazol-1-yl)-3-hydroxy-N,3-diphenylprop-2-enethioamide(compound 2) were synthesized and their structures were confirmed by means of IR, MS, 1H NMR, and elemental analysis. The structure of compound 1 was determined with single-crystal X-ray diffraction analysis. The results of the biological test show that the two compounds have a certain antifungal activity.