A mild and general method for the synthesis of (E) - 1,4 - dicarbonyl but - 2 - enes from 1,2 - diol oxidation - Wittig reaction - oxidation with manganese dioxide was developed with excellent yields. Seven target com-pounds were synthesized.%报道了一种温和的,以二氧化锰为氧化剂,通过串联氧化反应- Wittig 反应-氧化反应,一步制备(E)-1,3-二取代丙-2-烯-1-酮类化合物的合成方法。使用该方法,我们合成7个具有代表性的化合物。
展开▼