Global tissue and serum metabolomics reveals altered tumor biochemical activity in molecular subtypes of hepatocellular carcinoma and cholangiocarcinoma

摘要

＜正＞Objective:Cancer metabolite profiling（or cancer metabolomics）,the global view of the biochemical end products of cellular processes,is a promising approach to identify biomarkers and tumor subgroups,and to understand the biological mechanisms underlying cancer development and progression.Metabolites are the best molecular indicators