OBJECIVE To explore the distribution of estrogen receptors (ER) and progesterone receptors (PR) in patients with breast cancer and to compare the results with clinical parameters. METHODS Breast cancer specimens of 1393 cases were stained for the ER and PR by a SP Two-Step method, and analyzed with respect to age, menstrual status, histopathology and metastasis of axillary lymph nodes .RESULTS The correlation coefficients between ER and PR were positive (PO.05). There were significantly higher positive rates of ER and lower positive rates of PR in post-menopausal patients than in premenopausal cases(PO.05). The patients with no metastasis in the axillary lymph nodes had higher simultaneous positive rates of ER and PR (P展开▼
