以胸腔积液为首发表现及腺苷脱氨酶ADA显著增高为特点的淋巴瘤一例

摘要

目的 提高对淋巴瘤诊断的认识,评价不同病因所致的非结核性胸腔积液中腺苷脱氨酶(ADA)指标的水平.方法 回顾性分析1例以胸腔积液为首发表现、ADA显著增高为特点的淋巴瘤病例的临床表现及各类检查资料.结果 71岁男性,胸闷、气促1个月,首发表现为左侧胸腔大量积液,胸水ADA显著增高,最高达620.7 U/L,病理示弥漫性大B细胞淋巴瘤.结论 胸水ADA水平显著升高的不明原因胸腔积液,需要考虑到淋巴瘤的可能,应尽快完善病理学检查明确诊断.%Objective To improve the understanding of lymphoma and assess the adenosine deaminase( ADA) levels in nontuberculous pleural effusions of different aetiologies. Methods A case of lymphoma with high pleural effusion ADA levels as first symptom was retrospectively analysed, including clinical manifestation and examination. Results The male patient was 71 years old, had dyspnea for one month, with heavy pleural effusion in left as initial symptom. ADA levels of the pleural effusion were 620. 7 U/L. Finally, pleural biopsy was performed and pathology showed diffuse large B-cell lymphoma( DLBCL). Conclusions Lymphoma should be kept in mind in patients with high pleural effusion ADA levels, pathology examination should be taken in time to confirm diagnosis.