线粒体DNA含量变化在肿瘤诊断中的意义

摘要

各类常见的人类恶性肿瘤中的线粒体DNA含量变化,及其与肿瘤发生的潜在机制.探讨了线粒体DNA含量作为新的生物标志物在诊断肿瘤易感风险和早期监测方面的意义.%This review summarizes mtDNA content changes present in various types of common human malignancies and briefly describe its potential relation to the carcinogenic process. The review states the value of altered mtDNA content to be utilized as a diagnostic biomarker for identifying risk of cancer and early surveillance program.